Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep158 | Endocrine-Related Cancer | ECE2024

A new kind of hypophysitis: adverse effect of ICPIs

Torres Arroyo Belvis , Martinez Ana , Suarez Carolina , Maldonado Gonzalo , Gomez Jose , Angel Valero Miguel , Quiroga Ivan , Blanco Benito

Introduction: Hypophysitis is a rare disease. Lately, it is more frequent due to the use of Inmune Check Point Inhibitor (ICPIs). Ipilimumab or combo Ipilimumab + Nivolumab are the main cause. Agree with literature, 17-18% of the patients with these drugs suffer from. By contrast, with Idiopatic Autoimmune Hypophysitis and Lymphocytic Hypophysitis, this type of hypophysitis occurs in sixties men. Autoinmunity mechanism is known, but precise pathophysiology is unclear <p cl...